Autologous Stem Cell Harvesting & Processing
We perform minimally invasive bone marrow aspiration from the iliac crest or adipose tissue harvesting through mini-liposuction techniques. Our processing laboratory utilizes closed-system automated devices (Angel, Magellan) concentrating mesenchymal stem cells, platelets, and growth factors while maintaining cell viability and sterility. Final products undergo quality control testing including cell count, viability, and sterility verification.
Precision Delivery Under Imaging Guidance
We deliver stem cell preparations under ultrasound, fluoroscopic, or arthroscopic guidance ensuring accurate placement into target tissues. For orthopedic applications, we target specific anatomical structures (tendons, ligaments, cartilage, joints). For wound healing, we employ periwound injection techniques and topical applications with specialized delivery systems maximizing cellular retention and integration.
Orthopedic & Musculoskeletal Applications
We treat osteoarthritis (knee, hip, shoulder, ankle), tendinopathies (rotator cuff, Achilles, tennis elbow), ligament injuries, and cartilage defects. Our protocols include precise anatomical targeting, appropriate cell concentrations (5-50 million cells depending on indication), and combination with platelet-rich plasma or hyaluronic acid when indicated for synergistic effects.
Wound Healing & Regenerative Applications
For Advanced wounds, we apply stem cells through injection around wound edges, incorporation into scaffolds, or topical application with specialized dressings. We treat diabetic foot ulcers, venous ulcers, pressure injuries, and radiation-induced wounds. Our protocols include appropriate wound bed preparation and concurrent standard therapies maximizing regenerative potential.
- Comprehensive patient evaluation and appropriate candidate selection
- Minimally invasive stem cell harvesting with local anesthesia
- Closed-system processing with quality control verification
- Precision delivery under appropriate imaging guidance
- Standardized protocols for specific clinical indications
- Comprehensive postoperative care and rehabilitation protocols
- Regular follow-up with objective outcome measures
- Documentation of safety and efficacy through standardized reporting
Evidence-supported applications include osteoarthritis (knee, hip), tendinopathies (rotator cuff, Achilles), Advanced wounds (diabetic foot ulcers, venous ulcers), and certain degenerative conditions. Research applications (not yet standard) include cardiac repair, neurological conditions, and autoimmune diseases. We strictly adhere to evidence-based applications with documented safety and efficacy profiles.
Stem cells work through multiple mechanisms: differentiation into tissue-specific cells, paracrine signaling releasing growth factors and cytokines, immunomodulation reducing inflammation, angiogenesis promotion improving blood supply, and recruitment of endogenous stem cells. This multifactorial approach addresses the complex pathophysiology of degenerative conditions and Advanced wounds.
Most procedures involve 1-3 days of rest with gradual return to activities over 1-2 weeks. Initial improvements may be noted within 4-6 weeks as inflammation decreases, with progressive improvement over 3-6 months as tissue remodeling occurs. Maximum benefits are typically observed at 6-12 months post-procedure. We provide specific rehabilitation protocols for each application.
Duration varies by condition: osteoarthritis treatments may provide 2-5 years of benefit, tendinopathies often show sustained improvement at 1-2 years, while wound healing effects are typically permanent if underlying causes are addressed. Repeat treatments may be considered based on clinical response and disease progression, typically no sooner than 12 months after initial treatment.
Autologous stem cells from bone marrow or fat have excellent safety profiles with complication rates <1% for minor issues (pain, swelling) and serious complications extremely rare (<0.1%). We avoid systemic delivery, utilize precise anatomical targeting, maintain strict sterile technique, and conduct comprehensive screening excluding inappropriate candidates (active cancer, severe comorbidities, unrealistic expectations).
Our Team
Meet the Experts Behind Your Care
Dr. Viswanath Atreyapurapu
Consultant Vascular & Endovascular Surgeon
Dr. Manikanth Karumuri
Consultant Plastic, Reconstructive & Cosmetic SurgeonTestimonials
What Our Patients Are Saying
“I recently underwent vein laser treatment at IKIGAI under the care of Dr. Vishvanath Atreyapuram, and I am incredibly impressed with the experience and results. From the moment I stepped into the clinic, the staff made me feel welcome and at ease. Dr. Vishvanath is not only highly skilled and professional but also took the time to explain the procedure in detail, addressing all my concerns patiently.”
“My daughter was born with cleft palate and was advised to get operated after she turns 1 year old. We have lost all our hopes and were very worried about her. Dr K. Manikanth garu has done palatoplasty for my daughter last year. Since then he has taken very good care of my daughter even after the surgery and during reviews also, and now my daughter is perfectly alright. Thanks alot for Dr. Manikanth garu for the treatment.”
“Ikigai clinics is offering expert surgical care for all vascular and plastic surgery related conditions. It offers a serene ambience, world class infrastructure and highly skilled surgeons with personalized treatment plan for every patient. Highly recommended👍”
“I recently underwent vein laser treatment at IKIGAI under the care of Dr. Vishvanath Atreyapuram, and I am incredibly impressed with the experience and results. From the moment I stepped into the clinic, the staff made me feel welcome and at ease. Dr. Vishvanath is not only highly skilled and professional but also took the time to explain the procedure in detail, addressing all my concerns patiently.”
“I had a great experince with Dr viswanath Atreya and Dr manikanth karumuri for my varicose veins and venous ulcers treatment at ikigai clinics. From the very first consultation ,the doctor was kind ,through and extremely knowledgeable .iam so greatful for the care i recived and would highly recommend Dr viswanath and Dr manikanth to anyone dealing with varicose veins and venous ulcers Thank you ikigai clinics”
“⭐⭐⭐⭐⭐ Highly Recommend Ikigai Clinic for Nose Plastic Surgery! I recently had a nose plastic surgery at Ikigai Clinic, The entire experience, from consultation to post-surgery care, was handled with utmost professionalism and expertise. I'm truly satisfied with my results, and I highly recommend Ikigai Clinic to anyone considering cosmetic procedures. Thank you so much (Dr.Manikanth Karumuri)”
“I recently underwent AVF surgery with Dr. Viswanath Atreyapurapu at Ikigai Clinics, and I couldn’t be more satisfied with the care I received. Dr. Viswanath was incredibly professional, patient, and knowledgeable. He took the time to explain the procedure thoroughly and made me feel at ease every step of the way. The surgery went smoothly, and the post-operative care was excellent. Highly recommend Dr. Viswanath and Ikigai Clinics to anyone in need of vascular care.”